Guided antiplatelet therapy with P2Y12 antagonists in patients undergoing percutaneous coronary intervention: 3 systematic reviews with meta-analyses of randomized controlled trials with homogeneous design

Abstract excerpt

<h4> ABSTRACT </h4> <h4>Background</h4> Conflicting results were reported by randomized controlled trials (RCTs) exploring guided therapy (GT) with anti-P2Y12 drugs in patients undergoing percutaneous coronary intervention (PCI). Meta-analyses of RCTs failed to clearly identify what GT strategy, if any, is effective, because they lumped together RCTs with heterogeneous designs, comparing either genotype-GT or plat...

Topics

Open a Topic to create a Post that cites this publication.

• Blood Platelets
• Hemorrhage
• Percutaneous Coronary Intervention
• Platelet Aggregation Inhibitors
• Platelet Function Tests
• Purinergic P2Y Receptor Antagonists
• Randomized Controlled Trials as Topic
• Receptors, Purinergic P2Y12

Identifiers and source

Literature Corpus work

5e842ba8-4e9b-59f1-846f-4c867eb00e9b

DOI

10.1101/2023.05.25.23290520