Article

An equine Endothelin 3 cis-regulatory variant links blood pressure modulation to elite racing performance

2022-11-04

Abstract excerpt

A previous selective sweep analysis of horse racing performance revealed a 19.6 kb candidate region approximately 50 kb downstream of the Endothelin 3 ( EDN3 ) gene. EDN3 and other endothelin family members are associated with blood pressure regulation in humans and other species, but similar association studies in horses are lacking. We hypothesized that the sweep region includes a regulatory element acting on...

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Literature Corpus work: 5e6ed0f9-64fb-561b-827e-e5a032efa174
DOI: 10.1101/2022.11.04.515141

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