Article
Genome-wide analysis reveals selection for important traits in domestic horse breeds.
PLoS genetics - 1 Jan 2013
Petersen Jessica L, Mickelson James R, Rendahl Aaron K, Valberg Stephanie J, Andersson Lisa S, Axelsson Jeanette, Bailey Ernie, Bannasch Danika, Binns Matthew M, Borges Alexandre S, Brama Pieter, da Câmara Machado Artur, Capomaccio Stefano, Cappelli Katia, Cothran E Gus, Distl Ottmar, Fox-Clipsham Laura, Graves Kathryn T, Guérin Gérard, Haase Bianca, Hasegawa Telhisa, Hemmann Karin, Hill Emmeline W, Leeb Tosso, Lindgren Gabriella, Lohi Hannes, Lopes Maria Susana, McGivney Beatrice A, Mikko Sofia, Orr Nicholas, Penedo M Cecilia T, Piercy Richard J, Raekallio Marja, Rieder Stefan, Røed Knut H, Swinburne June, Tozaki Teruaki, Vaudin Mark, Wade Claire M, McCue Molly E
Abstract excerpt
Intense selective pressures applied over short evolutionary time have resulted in homogeneity within, but substantial variation among, horse breeds. Utilizing this population structure, 744 individuals from 33 breeds, and a 54,000 SNP genotyping array, breed-specific targets of selection were identified using an F(ST)-based statistic calculated in 500-kb windows across the genome. A 5.5-Mb region of ECA18, in...
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