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Article

Sequence analysis of the equine ACTN3 gene in Australian horse breeds.

Gene - 15 Mar 2014

Thomas K C, Hamilton N A, North K N, Houweling P J

Abstract excerpt

The sarcomeric α-actinins, encoded by the genes ACTN2 and ACTN3, are major structural components of the Z-line and have high sequence similarity. α-Actinin-2 is present in all skeletal muscle fibres, while α-actinin-3 has developed specialized expression in only type 2 (fast, glycolytic) fibres. A common single nucleotide polymorphism (SNP) in the human ACTN3 gene (R577X) has been found to influence muscle...

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Identifiers

PMID: 24440781
DOI: 10.1016/j.gene.2014.01.014

Genes

ACTN3
ACTN2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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