Article

Molecular determinants of Yellow Fever Virus pathogenicity in Syrian Golden Hamsters: one mutation away from virulence

2018-01-31

Abstract excerpt

<h4>ABSTRACT</h4> Yellow fever virus ( Flavivirus genus) is an arthropod-borne pathogen which can infect humans, causing a severe viscerotropic disease with a high mortality rate. Adapted viral strains allow the reproduction of yellow fever disease in hamsters with features similar to the human disease. Here, we used the Infectious Subgenomic Amplicons reverse genetics method to produce an equivalent to the hams...

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Literature Corpus work: 5e60c1cf-d7f6-505e-bc08-e2c8937245ef
DOI: 10.1101/249383

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