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An epigenetic clock for human skeletal muscle

17 Feb 2020

Abstract excerpt

BACKGROUND: Ageing is associated with DNA methylation changes in all human tissues, and epigenetic markers can estimate chronological age based on DNA methylation patterns across tissues. However, the construction of the original pan-tissue epigenetic clock did not include skeletal muscle samples and hence exhibited a strong deviation between DNA methylation and chronological age in this tissue. METHODS: To...

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PMID: 32067420
DOI: 10.1002/jcsm.12556

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