Article

Joint tissue explant model using psoriatic arthritis synovial fluid as a tool to capture patient-specific responses to treatments

2026-07-08

Abstract excerpt

<h4>Objective</h4> We developed a patient- and joint-specific explant co-culture system to model active psoriatic arthritis (PsA) and capture donor-specific tissue responses to therapeutic interventions. <h4>Methods</h4> Based on convergent joint pathology between end-stage osteoarthritis (OA) and PsA, OA cartilage-bone and synovium tissues from arthroplasty patients were exposed to synovial fluid (SF) obtained...

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Literature Corpus work: 5e52368e-6dfd-5826-b1d6-2e2d19dc2e60
DOI: 10.64898/2026.07.05.736607

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