Article

Ranitidine use, N-Nitrosodimethylamine (NDMA) production and variations in cancer diagnoses

2021-01-29

Abstract excerpt

<h4>Introduction</h4> Ranitidine is a member of the H 2 -blocker class of medications, commonly used in the treatment gastroesophageal reflux and peptic ulcer disease. Recent laboratory analyses have demonstrated that ranitidine may yield the probable carcinogen, N-Nitrosodimethylamine (NDMA). Here, we characterized the kinetics of NDMA production from ranitidine under various simulated gastric conditions. Moreove...

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Literature Corpus work: 5e4ffb13-ce3b-5be3-930c-f4552e775529
DOI: 10.1101/2021.01.27.21250656

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