Article

Transcriptomic Fingerprint of Bacterial Infection in Lower Extremity Ulcers

2021-12-25

Abstract excerpt

Clinicians and researchers utilize subjective classification systems based on clinical parameters to stratify lower extremity ulcer infections for treatment and research. This study compared clinical infection classifications (mild to severe) of lower extremity ulcers (n = 44) with transcriptomic profiles and direct measurement of bacterial RNA signatures by RNA-sequencing. Samples demonstrating similar transcript...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5dc19f15-76b6-51df-9b5b-a3f1764f7741
DOI: 10.1101/2021.12.20.21267962

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Transcriptomic Fingerprint of Bacterial Infection in Lower Extremity UlcersDOI 10.1101/2021.12.20.21267962Read

Single-cell RNA sequencing and transcriptomic analysis reveal the critical signatures involved in nonhealing diabetic foot ulcersSemantic proximity Read

Comprehensive transcriptomic analysis of immune-related genes in diabetic foot ulcers: New insights into mechanisms and therapeutic targetsSemantic proximity Read

A multiomics approach to identify host-microbe alterations associated with infection severity in diabetic foot infections: a pilot studySemantic proximity Read

Transcriptomic identification of genes expressed in invasive S. aureus diabetic foot ulcer infectionSemantic proximity Read

Single-Cell Analysis Reveals Major Histocompatibility Complex II‒Expressing Keratinocytes in Pressure Ulcers with Worse Healing OutcomesSemantic proximity Read

Molecular characterization of chronic cutaneous wounds reveals subregion‐ and wound type‐specific differential gene expressionSemantic proximity Read

Single Cell Transcriptomic Landscape of Diabetic Foot UlcersSemantic proximity Read

Single cell transcriptomic landscape of diabetic foot ulcersSemantic proximity Read

Single-cell analysis reveals MHCII expressing keratinocytes in pressure ulcers with worse healing outcomesSemantic proximity Read

A potential XGBoost Diagnostic Score for Staphylococcus aureus bloodstream infectionSemantic proximity Read

HERITABLE TISSUE-SPECIFIC GENE EXPRESSION ASSOCIATES WITH CHRONIC WOUND MICROBIAL SPECIESSemantic proximity Read

Identification of SASP-associated biomarkers and regulatory mechanisms in diabetic foot ulcers based on transcriptomics and experimental validationSemantic proximity Read