Article

Single-cell analysis reveals MHCII expressing keratinocytes in pressure ulcers with worse healing outcomes

2021-04-21

Abstract excerpt

Pressure ulcer (PU) is a chronic wound often seen in spinal cord injury patients and other bed-bound individuals, particularly in the elderly population. Despite its association with high mortality, the pathophysiology of PU remains poorly understood. Here, we compared single-cell transcriptomic profiles of human epidermal cells from PU wound edges with those from uninjured skin and acute wounds (AWs) in healthy d...

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Literature Corpus work: d56ff89b-b306-59a9-8f56-bd6b5ae9ca5a
DOI: 10.1101/2021.04.20.440591

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