Article

Mucosal TLR2-activating protein-based vaccination induces potent pulmonary immunity and protection against SARS-CoV-2 in mice

2022-01-05

Abstract excerpt

<title>Abstract</title> <p>Current vaccines against SARS-CoV-2 substantially reduce mortality, but protection against infection is less effective. Enhancing immunity in the respiratory tract, <italic>via</italic> mucosal vaccination, may provide protection against infection and minimise viral spread. We tested a novel subunit vaccine in mice, consisting of SARS-CoV-2 Spike protein with a TLR2-stimulating adjuvant...

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Literature Corpus work: 5d99c481-95d6-5fff-a5dc-1cc168c8b084
DOI: 10.21203/rs.3.rs-1179181/v1

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