Article

B and T cell phenotype and function in children with perinatally acquired HIV-1 infection

2013-01-01

Abstract excerpt

Untreated HIV infection is well known to have profound effects on CD4 T cell phenotype and function, ultimately leading to CD4 T cell depletion, AIDS and death. HIV is also known to affect B cell function and phenotype, resulting in impaired and dysregulated humoral immunity. Studies in HIV infected adults have demonstrated that Highly Active Antiretroviral Therapy (HAART) only partially restores B cell phenotype...

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Literature Corpus work: 5d896d60-c053-561c-b896-111cbd158630
DOI: 10.25560/11048

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