Article
HIV disease in children is associated with a selective decrease in CD23+ and CD62L+ B cells.
Clinical immunology and immunopathology - 1 Nov 1996
Rodriguez C, Thomas J K, O'Rourke S, Stiehm E R, Plaeger S
Abstract excerpt
We characterized the surface phenotype of B cells from HIV+ children in order to better understand the biology of B cell dysregulation. Twenty-nine HIV-infected, twenty-one exposed, and nineteen age-matched control children were studied for expression of CD5, CD10, CD21, CD23, CD25, CD62L, CD71, and CD69. We conclude that, despite persistent high immunoglobulin levels, total B cells decreased as HIV disease...
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