Article
Highly expressed miR-375 is not an intracellular oncogene in Merkel cell polyomavirus-associated Merkel cell carcinoma
2019-10-22
Abstract excerpt
miR-375 is a highly abundant miRNA in Merkel cell carcinoma (MCC), in other cancers it acts either as a tumor suppressor or oncogene. While free-circulating miR-375 serves as surrogate marker for tumor burden in patients with advanced MCC, its function within MCC cells has not been established. Nearly complete miR-375 knockdown in MCC cell lines was achieved using antagomiRs via nucleofection. Neither cell viabili...
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Identifiers and source
- Literature Corpus work
- 5d82db9f-d5f2-5d22-8769-72e939b306e6
- DOI
- 10.1101/813378