Article

Comparison of In Vitro Models for Drug-Induced Liver Injury Assessment

2024-05-10

Abstract excerpt

Drug-induced liver injury (DILI) stands as a significant cause of drug attrition. To mitigate clinical DILI risks, assessing drugs using human liver models is crucial since animal studies may fall short due to species-specific liver pathway variations. Cell-based preclinical hepatotoxicity testing is often pertinent. In the present study, cells from a human liver cancer line (HepG2, HepaRG) were cultured in both f...

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Literature Corpus work: 5d17e937-8c46-578d-9047-3fc9c7ea3c13
DOI: 10.20944/preprints202405.0676.v1

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