Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Modeling drug-induced liver injury: current status and future prospects

2 Sept 2022

Abstract excerpt

Introduction Idiosyncratic drug-induced liver injury (iDILI) is a challenging and unpredictable multifactorial condition. At present, validated preclinical models for the prediction of the hepatotoxic potential of a given drug are scarce.Areas covered This review intends to sum up the current knowledge about in vitro (including hepatocyte 2D cultures, cocultures with non-parenchymal cells, 3D configurations and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drug-Induced Hepatotoxicity and Protection
Share to Liver physiology and pathology
Share to Pharmacogenetics and Drug Metabolism

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36107152
DOI: 10.1080/17425255.2022.2122810

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Modeling drug-induced liver injury: current status and future prospectsPMID 36107152Read ↗

Toxicogenomics of drug induced liver injury – from mechanistic understanding to early prediction.Semantic proximity Read ↗

Current Concepts of Mechanisms in Drug-Induced HepatotoxicitySemantic proximity Read ↗

Investigating novel methods of enhancing in vitro models of drug induced liver injurySemantic proximity Read ↗

Drug-induced liver injury: a safety review.Semantic proximity Read ↗

Liver injury caused by drugs: an update.Semantic proximity Read ↗

Idiosyncratic Drug Hepatotoxicity Revisited: New Insights from Mechanistic ToxicologySemantic proximity Read ↗

Drug-induced liver injury: summary of a single topic clinical research conference.Semantic proximity Read ↗

Idiosyncratic drug-induced liver injury: an update on the 2007 overview.Semantic proximity Read ↗

Drug-Induced Liver Injury: Insights from Genetic StudiesSemantic proximity Read ↗

Immune-Mediated Drug-Induced Liver Injury: Immunogenetics and Experimental Models.Semantic proximity Read ↗

Mechanisms of drug-induced liver injurySemantic proximity Read ↗

Pathogenesis of idiosyncratic drug-induced liver injury and clinical perspectives.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.