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Deletions of pfhrp2 and pfhrp3 genes were uncommon in rapid diagnostic test-negative Plasmodium falciparum isolates from Uganda

2020-12-29

Abstract excerpt

<h4>Background: </h4> Rapid diagnostic tests (RDTs) play a key role in malaria case management. The most widely used RDT identifies Plasmodium falciparum based on immunochromatographic recognition of P. falciparum histidine-rich protein 2 (PfHRP2). Deletion of the paralogous pfhrp2 and pfhrp3 genes leads to false-negative PfHRP2-based RDTs, and has been reported in P. falciparum infections from South America and A...

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Literature Corpus work
5d061424-72d5-50d8-b32d-69b69f73efee
DOI
10.21203/rs.3.rs-42855/v2
Open publication

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