Article

The effect of cold ischemia time on hypoxia, EMT, and apoptosis pathways in normal colon mucosa

2025-03-13

Abstract excerpt

Cold ischemia time (CIT), the interval between tissue excision and preservation, is a critical preanalytical variable that profoundly impacts gene expression profiles. Variability in CIT can lead to inconsistent transcriptomic results, making study interpretation challenging and undermining reproducibility in biomedical research. Our study aimed to evaluate the impact of CIT on the expression of cancer-related gen...

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Literature Corpus work: 5c9b9bda-ede9-5cf9-a4a4-a4df840e1350
DOI: 10.1101/2025.03.09.642255

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