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Article

Effects of Delay in the Snap Freezing of Colorectal Cancer Tissues on the Quality of DNA and RNA

1 Jan 2010

Abstract excerpt

PURPOSE: The success of basic molecular research using biospecimens strongly depends on the quality of the specimen. In this study, we evaluated the effects of delayed freezing time on the stability of DNA and RNA in fresh frozen tissue from patients with colorectal cancer. METHODS: Tissues were frozen at 10, 30, 60, and 90 minutes after extirpation of colorectal cancer in 20 cases. Absorbance ratio of 260 to 280...

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Identifiers

PMID: 21152133
DOI: 10.3393/jksc.2010.26.5.316

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