Article

Functional annotation with expression validation identifies novel metastasis-relevant genes from post-GWAS risk loci in sporadic colorectal carcinomas

2023-06-16

Abstract excerpt

Colorectal cancer (CRC) is the third highest incidence cancer and leading cause of cancer mortality worldwide. Metastasis to distal organ is the major cause of cancer mortality. However, the underlying genetic factors are unclear. This study aims to identify metastasis-relevant genes and pathways for better management of metastasis-prone patients. Multiple lines of evidence have indicated that germline variants pl...

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Literature Corpus work: 5c527537-5b39-5bc6-b85b-8fe671d60e9b
DOI: 10.1101/2023.06.13.23291271

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