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Glucosodiene as a Non-Enzymatically Generated Glucose-Derived Glycosidic System: Multi-Scale Reprogramming of the Glycolysis–pH–Glycocalyx Network from Molecular Design to Nanotechnology-Enabled Translational Oncology

2026-04-22

Abstract excerpt

<h4>Background: </h4> and Purpose: Tumor progression is sustained by a tightly coupled biochemical network linking aerobic glycolysis, extracellular acidification, and glycocalyx-dependent membrane signaling. This study evaluates glucosodiene, a non-enzymatically generated glucose-derived glycosidic system, as a multi-axis perturbant capable of simultaneously modulating metabolic flux, pH homeostasis, and glycan a...

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Literature Corpus work
5c3bb05d-fb46-5d23-9fe4-033997a2fe04
DOI
10.20944/preprints202604.1565.v1
Open publication

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Glucosodiene as a Non-Enzymatically Generated Glucose-Derived Glycosidic System: Multi-Scale Reprogramming of the Glycolysis–pH–Glycocalyx Network from Molecular Design to Nanotechnology-Enabled Translational OncologyDOI 10.20944/preprints202604.1565.v1
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