Article

Unlabeled salivary gland organoids have distinct Raman signatures following FGF2-induced proacinar cell differentiation

2021-09-16

Abstract excerpt

Organoids are self-organized three-dimensional (3D) tissue cultures that model the structure and function of organs to provide insights into signaling during organ formation and have translational applications in disease modeling and assessing drug responses. Due to their heterogeneity, there is a need for non-destructive methods to identify the differentiation state, or the phenotype, of organoids. As organoids o...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5bbe808b-673f-5419-90ba-16a19db6d645
DOI: 10.1101/2021.09.16.460651

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Unlabeled salivary gland organoids have distinct Raman signatures following FGF2-induced proacinar cell differentiationDOI 10.1101/2021.09.16.460651Read

Raman microspectroscopy fingerprinting of organoid differentiation state.Semantic proximity Read

Histologically resolved spatial multi-omics of human oral squamous cell carcinomaSemantic proximity Read

Human iPSC-derived salivary gland organoids model diabetic salivary gland dysfunctionSemantic proximity Read

scRNAseq of healthy and irradiated mouse parotid glands highlights crosstalk between immune and secretory cells during chronic injurySemantic proximity Read

Identifying Fibrogenic Cells Following Salivary Gland Obstructive InjurySemantic proximity Read

Bottom-up assembly of salivary gland microtissues for assessing myoepithelial cell function.Semantic proximity Read

Label-Free Optical Biopsy Reveals Biomolecular and Morphological Features of Diabetic Kidney Tissue in 2D and 3DSemantic proximity Read

Identification of abnormal stem cells using Raman spectroscopy.Semantic proximity Read

FGFR2b is essential for salivary gland duct homeostasis and MAPK-dependent seromucous acinar cell differentiationSemantic proximity Read

Biomolecular phenotyping and heterogeneity assessment of mesenchymal stromal cells using label-free Raman spectroscopy.Semantic proximity Read

Quantitative Phenotypic Image Analysis of Three-Dimensional Organotypic Cultures.Semantic proximity Read

Extracellular Vesicles of Salivary Mesenchymal Stem Cells Mitigate Acute Irradiation Injury: Use of an ex-vivo organotypic human slice tissue culture as a disease modelSemantic proximity Read