Article
Raman microspectroscopy fingerprinting of organoid differentiation state.
Cellular & molecular biology letters - 28 Jun 2022
Tubbesing Kate, Moskwa Nicholas, Khoo Ting Chean, Nelson Deirdre A, Sharikova Anna, Feng Yunlong, Larsen Melinda, Khmaladze Alexander
Abstract excerpt
BACKGROUND: Organoids, which are organs grown in a dish from stem or progenitor cells, model the structure and function of organs and can be used to define molecular events during organ formation, model human disease, assess drug responses, and perform grafting in vivo for regenerative medicine approaches. For therapeutic applications, there is a need for nondestructive methods to identify the differentiation...
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