Article

Druggable sites identification in Streptococcus mutans VicRK system evaluated by catechols

2022-07-04

Abstract excerpt

<h4>Background: </h4> Dental caries is a global public health problem, being the most common non-communicable disease. Streptococcus mutans is the causative agent that develops cariogenic dental biofilms in humans due to its ability to produce glycosyltransferases (Gtfs). These Gtfs act in the exopolysaccharides synthesis (EPS) that form biofilms. The gene expression encoding Gtfs is modulated by the VicRK system...

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Literature Corpus work: 5bbe7e8f-437c-5ae5-bd27-476dfe62d6f3
DOI: 10.22541/au.165695403.36126711/v1

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