Article

Robustness increases heritability: implications for familial disease

2022-08-18

Abstract excerpt

Robustness protects organisms in two ways. Homeostatic buffering lowers the variation of traits caused by internal or external perturbations. Tolerance reduces the consequences of bad situations, such as extreme phenotypes or infections. This article shows that both types of robustness increase the heritability of protected traits. Additionally, robustness strongly increases the heritability of disease. Perhaps th...

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Literature Corpus work: 5b9c6c8d-4e92-53f9-9a25-0d3d1cdb7618
DOI: 10.1101/2022.08.18.504431

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