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Systems Biology of Phenotypic Robustness and Plasticity.

Integrative and comparative biology - 1 Aug 2017

Nijhout H Frederik, Sadre-Marandi Farrah, Best Janet, Reed Michael C

Abstract excerpt

SYNOPSIS: Gene regulatory networks, cellular biochemistry, tissue function, and whole body physiology are imbued with myriad overlapping and interacting homeostatic mechanisms that ensure that many phenotypes are robust to genetic and environmental variation. Animals also often have plastic responses to environmental variables, which means that many different phenotypes can correspond to a single genotype. Since...

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PMID: 28859407
DOI: 10.1093/icb/icx076

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