Article

A Milroy Disease Family Caused by FLT4 Gene Mutation of c.2774 T>A

2021-01-04

Abstract excerpt

<h4>Background: </h4> Milroy disease (MD) is a rare, autosomal dominant disorder. Mutations in the Fms-related tyrosine kinase 4 ( FLT4 ) gene cause the symptoms of this disease. In this report, we investigated the mutations in a large Chinese family with MD. <h4>Methods: </h4>: We conducted Sanger sequencing of exons 17–26 of the FLT4 (NM_182925.4) gene. The primers were as follows: forward, 5' CTTCATCAGCGTCGAGTG...

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Literature Corpus work: 5b971deb-859b-5b65-a857-b3c4243c5b72
DOI: 10.21203/rs.3.rs-129626/v1

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