Article

A Milroy Disease Family Caused by FLT4 Gene Mutation of c.2774 T>A with Phenotypes Heterogeneity

2020-10-05

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Milroy disease is a rare, autosomal dominant disorder. Mutations of <italic>FLT4</italic> (Fms Related Tyrosine Kinase 4) gene impaired tyrosine kinase signaling, and further cause symptoms of Milroy disease. In this research, we found a large Chinese MD family with phenotype heterogeneities. And we conducted Next Generation Sequencing analysis to explore possib...

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Literature Corpus work: a5624b7b-d858-5c11-be55-b5f43c234417
DOI: 10.21203/rs.3.rs-44896/v1

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