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Article

A novel FLT4 mutation identified in a patient with Milroy disease.

Lymphology - 1 Mar 2014

DiGiovanni R M, Erickson R P, Ohlson E C, Bernas M, Witte M H

Abstract excerpt

Milroy disease is an autosomal dominant disorder generally presenting with below the knee lymphedema at birth. It is linked to mutations in the tyrosine kinase domain of the VEGFR3 protein which is encoded in the FLT4 gene. Here we report a case of Milroy disease in a patient with a dominant pattern of inheritance, classical physical findings, and lymphatic system imaging demonstrating lack of tracer transport in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Vascular Endothelial Growth Factor Receptor-3

Source

Identifiers

PMID: 25109169

Genes

FLT4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A novel FLT4 mutation identified in a patient with Milroy disease.PMID 25109169Read ↗

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