Article
Development of a replication competent murine norovirus reporter system
2025-01-16
Abstract excerpt
Caliciviruses are significant agricultural and human pathogens that are poorly understood due to the dearth of molecular tools, including reporter systems. We report the development of a stable, faithful, and robust luciferase-based reporter system for a model calicivirus, murine norovirus (MNoV). Genetic insertion of a HiBiT tag, an 11 amino acid fragment of nanolucifersase, at the junction of the nonstructural p...
Topics
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- Animal Virus Infections Studies
- Mosquito-borne diseases and control
- RNA and protein synthesis mechanisms
- Viral gastroenteritis research and epidemiology
- Viral Infections and Immunology Research
- Viral Infections and Vectors
- Viral Infectious Diseases and Gene Expression in Insects
- Virus-based gene therapy research
Identifiers and source
- Literature Corpus work
- cd21e89d-10bd-5fb6-8877-311c983b3289
- DOI
- 10.1101/2025.01.15.633260