Article

Ultrastructural analysis of prostate cancer tissue provides insights into androgen-dependent adaptations to membrane contact site establishment

2023-05-12

Abstract excerpt

Membrane trafficking and organelle contact sites are important for regulating cell metabolism and survival; processes often deregulated in cancer. Prostate cancer is the second leading cause of cancer-related death in men in the developed world. While early-stage disease is curable by surgery or radiotherapy there is an unmet need to identify prognostic biomarkers, markers to treatment response and new therapeutic...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5b18c05f-8591-58c2-9f4c-93745bda1a31
DOI: 10.1101/2023.05.10.540238

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Ultrastructural analysis of prostate cancer tissue provides insights into androgen-dependent adaptations to membrane contact site establishmentDOI 10.1101/2023.05.10.540238Read

Mitochondrial Alterations in Prostate Cancer: Roles in Pathobiology and Racial DisparitiesSemantic proximity Read

Altered expression of vesicular trafficking machinery in prostate cancer affects lysosomal dynamics and provides insight into the underlying biology and disease progressionSemantic proximity Read

Therapy-induced lipid uptake and remodeling underpin ferroptosis hypersensitivity in prostate cancerSemantic proximity Read

Exploring STEAP1 Expression in Prostate Cancer Cells in Response to Androgen Deprivation and in Small Extracellular VesiclesSemantic proximity Read

The non-canonical mechanism of ER stress-mediated progression of prostate cancerSemantic proximity Read

A Spatiotemporal Atlas of Extranuclear Androgen Receptor Proximal Interaction NetworksSemantic proximity Read

Pauperization of Emerin from nuclear envelope during chromatin bridge resolution drives prostate cancer cell migration and invasivenessSemantic proximity Read

Inhibitors of vacuolar ATPase proton pumps inhibit human prostate cancer cell invasion and prostate-specific antigen expression and secretion.Semantic proximity Read

Targeting membrane androgen receptors in tumorsSemantic proximity Read

High mitochondria content is associated with prostate cancer disease progressionSemantic proximity Read

Topology of NGEP, a Prostate-Specific Cell:Cell Junction Protein Widely Expressed in Many Cancers of Different Grade LevelSemantic proximity Read

Reversal of chemosensitivity and induction of cell malignancy of a non-malignant prostate cancer cell line upon extracellular vesicle exposure.Semantic proximity Read