Article

Oncogenic effects of germline mutations in lysosomal storage disease genes

2018-07-30

Abstract excerpt

Clinical observations have indicated that patients with Gaucher disease or Fabry disease are at increased risk of cancer. However, a systematic evaluation of the oncogenic effects of causal mutations of lysosomal storage diseases (LSDs) has been lacking. Here we report a comprehensive association analysis between potentially pathogenic germline mutations in LSD genes and cancer interrogating genomic (or exomic) va...

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Literature Corpus work: 5ae9eb57-c6f0-53d9-bd74-c3fb34a17782
DOI: 10.1101/380121

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