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Article

UHMK1 Dependent Phosphorylation of Cajal Body Protein Coilin Altered 5-FU Sensitivity in Colon Cancer Cells

2021-08-02

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Resistance to 5-fluorouracil (5-FU) in chemotherapy and recurrence of colorectal tumors is a serious problem to be resolved for the improvement of clinical outcomes.<bold>Methods: </bold>In the present study, the effects of conditioned medium (CM) derived from 5-FU-resistant HCT-8/FU on cell functions were evaluated. The methods of immunofluorescence and RNA-seq...

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Literature Corpus work
5ac08c74-4cc7-503d-8565-e759d0896746
DOI
10.21203/rs.3.rs-753268/v1
Open publication

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UHMK1 Dependent Phosphorylation of Cajal Body Protein Coilin Altered 5-FU Sensitivity in Colon Cancer CellsDOI 10.21203/rs.3.rs-753268/v1
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