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Article

Hypoxia-Induced miR-675-5p Supports β-Catenin Nuclear Localization by Regulating GSK3-β Activity in Colorectal Cancer Cell Lines.

International journal of molecular sciences - 28 May 2020

Saieva Laura, Barreca Maria Magdalena, Zichittella Chiara, Prado Maria Giulia, Tripodi Marco, Alessandro Riccardo, Conigliaro Alice

Abstract excerpt

The reduction of oxygen partial pressure in growing tumors triggers numerous survival strategies driven by the transcription factor complex HIF1 (Hypoxia Inducible Factor-1). Recent evidence revealed that HIF1 promotes rapid and effective phenotypic changes through the induction of non-coding RNAs, whose contribution has not yet been fully described. Here we investigated the role of the hypoxia-induced, long...

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Identifiers

PMID: 32481626
DOI: 10.3390/ijms21113832
PMCID: PMC7312749

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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