Article

Nanoparticles Delivering Antagomir-483-5p to Bone Marrow Mesenchymal Stem Cells Prevent Osteoporosis by Increasing Bone Formation

2021-09-20

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Promoting bone marrow mesenchymal stem cell (BMSC) osteoblastic diﬀerentiation is a promising therapeutic strategy for osteoporosis (OP). The present study demonstrates that miR-483-5p inhibits the osteogenic differentiation of BMSCs. Therefore, selectively delivering the nanoparticles carrying antagomir-483-5p (miR-483-5p inhibitor) to BMSCs is expected to beco...

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Literature Corpus work: 5aa8e486-2bc9-52af-9425-0ef679d1a69e
DOI: 10.21203/rs.3.rs-882695/v1

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