Article

Predicting Immunotherapy Response Through Chemotherapy-Induced Tumor Microenvironment Remodeling

2026-06-11

Abstract excerpt

<h4>Background</h4> Chemotherapy before immunotherapy improves outcomes in multiple cancers, but the benefit is heterogeneous: only some tumors undergo the immune remodeling that makes subsequent immunotherapy effective, and no biomarker identifies these patients prospectively, leading to uniform use of chemo-immunotherapy and avoidable toxicity. <h4>Methods</h4> A random forest model of tumor-microenvironment (...

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Literature Corpus work: 5a11e44b-04f1-51ec-acd9-c60afaf32ad4
DOI: 10.64898/2026.06.08.730822

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