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Article

Core signaling pathways in ovarian cancer stem cell revealed by integrative analysis of multi-marker genomics data

3 May 2018

Abstract excerpt

Tumor recurrence occurs in more than 70% of ovarian cancer patients, and the majority eventually becomes refractory to treatments. Ovarian Cancer Stem Cells (OCSCs) are believed to be responsible for the tumor relapse and drug resistance. Therefore, eliminating ovarian CSCs is important to improve the prognosis of ovarian cancer patients. However, there is a lack of effective drugs to eliminate OCSCs because the...

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PMID: 29723215
DOI: 10.1371/journal.pone.0196351

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