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Elucidating the Pathogenesis of Pre-eclampsia Using In Vitro Models of Spiral Uterine Artery Remodelling

23 Oct 2017

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PURPOSE OF REVIEW: The aim of the study is to perform a critical assessment of in vitro models of pre-eclampsia using complementary human and cell line-based studies. Molecular mechanisms involved in spiral uterine artery (SUA) remodelling and trophoblast functionality will also be discussed. RECENT FINDINGS: A number of proteins and microRNAs have been implicated as key in SUA remodelling, which could be...

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PMID: 29063290
DOI: 10.1007/s11906-017-0786-2

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