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Prognostic models of immune-related cell death and stress unveil mechanisms driving macrophage phenotypic evolution in colorectal cancer

28 Jan 2025

Abstract excerpt

BACKGROUND: Tumor microenvironment (TME), particularly immune cell infiltration, programmed cell death (PCD) and stress, has increasingly become a focal point in colorectal cancer (CRC) treatment. Uncovering the intricate crosstalk between these factors can enhance our understanding of CRC, guide therapeutic strategies, and improve patient prognosis. METHODS: We constructed an immune-related cell death and stress...

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PMID: 39875913
DOI: 10.1186/s12967-025-06143-9

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