Article

Rapamycin rejuvenates oral health in aging mice

2019-12-10

Abstract excerpt

Periodontal disease is an age-associated disorder clinically defined by periodontal bone loss, inflammation of the specialized tissues that surround and support the tooth, and microbiome dysbiosis. Currently, there is no therapy for reversing periodontal disease, and treatment is generally restricted to preventive measures or tooth extraction. The FDA-approved drug rapamycin slows aging and extends lifespan in mul...

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Literature Corpus work: 59917350-f407-555e-8d9d-4dc7e5b4dcd3
DOI: 10.1101/861369

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