Article
Identification of Crucial Genes Associated with Ferroptosis in COPD via Comprehensive Bioinformatics Analysis and the Relevant Experimental Validation
2024-10-25
Abstract excerpt
<title>Abstract</title> <p><bold>Background:</bold> Chronic obstructive pulmonary disease (COPD) is a chronic respiratory disease characterized by partially reversible airway obstruction, with high mortality and disability rates. Smoking is the primary risk factor for COPD. Ferroptosis is a novel form of cell death characterized by iron-mediated lipid peroxidation induced by reactive oxygen species (ROS) generate...
Topics
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- Cancer-related molecular mechanisms research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Epigenetics and DNA Methylation
- Ferroptosis and cancer prognosis
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Neonatal Respiratory Health Research
- S100 Proteins and Annexins
- Single-cell and spatial transcriptomics
Identifiers and source
- Literature Corpus work
- dca072f6-ef55-5def-8e77-2be3cadf5adf
- DOI
- 10.21203/rs.3.rs-5315834/v1
