Article
Integrating RNA-seq and scRNA-seq to explore the mechanism of macrophage ferroptosis associated with COPD
9 Mar 2023
Abstract excerpt
Aims: Our study focused on whether macrophages ferroptosis is associated with the pathogenesis of chronic obstructive pulmonary disease (COPD) or not. Main methods: We first identified macrophage module genes by weighted gene co-expression network analysis (WGCNA) in RNA sequencing (RNA-seq) date from COPD, and then identified macrophage marker genes by comprehensive analysis of single-cell RNA sequencing...
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