Article

Li-Fraumeni Syndrome: An In-depth Overview

2025-09-10

Abstract excerpt

<h4>Introduction: </h4> to Li-Fraumeni Syndrome Li-Fraumeni Syndrome (LFS) is a rare, inherited disorder that significantly increases the risk of developing several types of cancer, often at a young age. First identified by Drs. Frederick Li and Joseph Fraumeni in 1969, LFS is caused by mutations in the TP53 gene, which encodes a protein crucial for regulating cell division and preventing tumor formation. When thi...

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Literature Corpus work: 58a0adf4-15a6-5191-826b-57f5464ecbad
DOI: 10.22541/au.175752861.10770307/v1

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