Article

Double heterozygous pathogenic variants in the BRCA1 and BRCA2 genes in a patient with bilateral metachronous breast cancer: a case report

2021-04-14

Abstract excerpt

<h4>Background: </h4> Double heterozygosity pathogenic variants in BRCA1 and BRCA2 genes are a very rare finding, particularly in non-Ashkenazi individuals. We described the first case of double heterozygosity variants in a non-Ashkenazi Argentinean woman with metachronous bilateral breast cancer. Case presentationThe proband is a 65-year-old female diagnosed with invasive ductal carcinoma in the left breast at 45...

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Literature Corpus work: 5897cdc2-03fc-5991-9095-b9736e845d1c
DOI: 10.21203/rs.3.rs-412077/v1

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