Article

Ancestry-associated immune signalling differences in atopic dermatitis and dupilumab treatment

2025-12-09

Abstract excerpt

<h4>Background</h4> Atopic dermatitis (AD) is a common atopic disease worldwide and dupilumab, a monoclonal antibody directing to the IL4/IL13 signalling, is emerging as an effective therapy for AD. Recently, there is report describing differences in AD severity and treatment responses to dupilumab among different geographic regions, but the underlying mechanisms remain unresolved. Patients’ ancestral backgrounds...

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Literature Corpus work: 588021d9-85fc-5f1b-82f4-09e64f0f7edd
DOI: 10.64898/2025.12.08.25341816

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