Back to search

Article

qRT-PCR-based DNA homologous recombination associated 4-gene score predicts pathologic complete response to platinum-based neoadjuvant chemotherapy in triple-negative breast cancer

2021-05-13

Abstract excerpt

<title>Abstract</title> <p><bold>Purpose</bold>Cumulative evidences suggested the addition of platinum agents as neoadjuvant chemotherapy (NACT) could improve pathologic complete response (pCR) in triple-negative breast cancers (TNBC). We tried to develop a DNA homologous recombination (HR) associated gene expression score to predict tumor sensitivity to platinum-based NACT in TNBC.<bold>Methods</bold>A retrospec...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
5865010b-2a04-5c13-bb38-045407b887a3
DOI
10.21203/rs.3.rs-335000/v2
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
qRT-PCR-based DNA homologous recombination associated 4-gene score predicts pathologic complete response to platinum-based neoadjuvant chemotherapy in triple-negative breast cancerDOI 10.21203/rs.3.rs-335000/v2
Predictive biomarkers for triple negative breast cancer treated with platinum-based chemotherapy.Semantic proximity
Association between homologous recombination deficiency and outcomes with platinum and platinum-free chemotherapy in patients with triple-negative breast cancerSemantic proximity
The Diagnostic Value of DNA Repair Gene in Breast Cancer Recurrence and MetastasisSemantic proximity
Gene expression signature for predicting homologous recombination deficiency in triple-negative breast cancerSemantic proximity
Applicability of Anticancer Drugs for the Triple-Negative Breast Cancer Based on Homologous Recombination Repair DeficiencySemantic proximity
Neo-Family History Score Is A Novel Biomarker of Pathological Complete Response, Safety, and Survival Outcomes In Patients With Breast Cancer Receiving Neoadjuvant Platinum-Based Chemotherapy: A Retrospective Analysis of Two Prospective TrialsSemantic proximity
Integrative Analysis of Homologous Recombination Repair Patterns Unveils Prognostic Signatures and Immunotherapeutic Insights in Breast CancerSemantic proximity
[Application value of DNA damage repair variants in adjuvant therapy of triple negative breast cancer].Semantic proximity
Adjuvant Chemotherapy Guidance for pT1-3N0-1 Breast Cancer Patients with HR+, HER2- subtype: a study based on SEER databaseSemantic proximity
AcornHRD: an HRD algorithm highly associated with anthracycline-based neoadjuvant chemotherapy in breast cancer in ChinaSemantic proximity
Identification of a Novel Gene Model-Based Homologous Recombination Deficiency Score to Improve Survival Prediction of TNBC.Semantic proximity
Gene expression signature for predicting homologous recombination deficiency in triple-negative breast cancerSemantic proximity
Select a neighboring publication to make it the new centre.