Article
Predictive biomarkers for triple negative breast cancer treated with platinum-based chemotherapy.
Cancer biology & therapy - 3 Jun 2017
Jin Juan, Zhang Wenwen, Ji Wenfei, Yang Fang, Guan Xiaoxiang
Abstract excerpt
Treatment of triple negative breast cancer (TNBC) has been a big challenge since it is defined. To date, platinum-based chemotherapy has played a significant role in the treatment of TNBC patients. However, some patients do not respond to platinum salts or gradually develop chemoresistance, resulting in little effect, or even some adverse effects. Here, we review numerous preclinical and clinical investigations...
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