Article

Preclinical development of non-viral gene therapy for patients with advanced pancreatic cancer

2022-12-15

Abstract excerpt

<h4>ABSTRACT</h4> Pancreatic ductal adenocarcinoma remains one of the greatest challenges in oncology for which therapeutic intervention is urgently needed. We demonstrated that the intratumoral gene transfer of somatostatin receptor 2, to combat tumor aggressiveness, or of deoxycytidine kinase and uridylate monophosphate kinase, to sensitize to gemcitabine chemotherapy, has antitumoral potential. Here, we descri...

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Literature Corpus work: 5858c450-3f30-50a2-98a2-7b400dd9f951
DOI: 10.1101/2022.12.13.520242

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