Article
Rexin-G, a targeted genetic medicine for cancer.
Expert opinion on biological therapy - 1 May 2010
Gordon Erlinda M, Hall Frederick L
Abstract excerpt
IMPORTANCE OF THE FIELD: Rexin-G, a tumor-targeted retrovector bearing a cytocidal cyclin G1 construct, is the first targeted gene therapy vector to gain fast track designation and orphan drug priorities for multiple cancer indications in the US. AREAS COVERED IN THIS REVIEW: This review describes the major milestones in the clinical development of Rexin-G: from the molecular cloning and characterization of the...
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