Article

Exploring the Binding Mechanism between Human Profilin (PFN1) and Polyproline-10 through Binding Mode Screening

2018-09-16

Abstract excerpt

The large magnitude of protein-protein interaction (PPI) pairs within the human interactome necessitates the development of predictive models and screening tools to better understand this fundamental molecular communication. However, despite enormous efforts from various groups to develop predictive techniques in the last decade, PPI complex structures are in general still very challenging to predict due to the la...

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Literature Corpus work: 57d9c1b2-58ce-556e-89d3-a4172e87f36f
DOI: 10.1101/418830

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